The Efficacy of Tocilizumab in the Treatment of Patients with Refractory Immune-Mediated Necrotizing Myopathies: An Open-Label Pilot Study

• Main Authors: Sizhao Li (Author), Wenli Li (Author), Wei Jiang (Author), Linrong He (Author), Qinglin Peng (Author), Guochun Wang (Author), Xin Lu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To evaluate the efficacy of tocilizumab (TCZ) in adult patients with refractory immune-mediated necrotizing myopathies (IMNMs) and investigate possible predictive biomarkers of the response to treatment with TCZ.Methods: Patients with refractory IMNM were enrolled in this open-label pilot...