Natural intestinal metabolite xylitol reduces BRD4 levels to mitigate renal fibrosis

• Main Authors: Zhouke Tan (Author), Ze Wang (Author), Qianglin Zeng (Author), Xiaoyou Liu (Author), Yamei Zhang (Author), Shujue Li (Author), Junlin Huang (Author), Yunong Zeng (Author), Zongshun Huang (Author), Can Jin (Author), Ningying Fu (Author), Qian Zhao (Author), Yingsong Mu (Author), Ziyi Wang (Author), Jie Xiao (Author), Hong Yang (Author), Guibao Ke (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Renal fibrosis is a typical pathological change from chronic kidney disease (CKD) to end‐stage renal failure, which presents significant challenges in prevention and treatment. The progression of renal fibrosis is closely associated with the "gut‐kidney axis," therefore, although...