Impact of Lowering TSH Cut-Off on Neonatal Screening for Congenital Hypothyroidism in Minas Gerais, Brazil

• Main Authors: Nathalia Teixeira Palla Braga (Author), Jáderson Mateus Vilela Antunes (Author), Enrico Antônio Colosimo (Author), Vera Maria Alves Dias (Author), José Nélio Januário (Author), Ivani Novato Silva (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A higher incidence of primary congenital hypothyroidism (CH) has been related to increased sensitivity in neonatal screening tests. The benefit of treatment in mild cases remains a topic of debate. We evaluated the impact of reducing the blood-spot TSH cut-off (b-TSH) from 10 (Group 2) to 6 mIU/L (G...