Chiral discrimination of amlodipine from pharmaceutical products using capillary electrophoresis

• Main Authors: Melania Cârcu-Dobrin (Author), Alexandra Georgiana Sabău (Author), Gabriel Hancu (Author), Gyéresi Árpád (Author), Aura Rusu (Author), Hajnal Kelemen (Author), Lajos Attila Papp (Author), Anca Cârje (Author)
• Format: Book
• Published: Universidade de São Paulo, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present work describes the development of a capillary electrophoresis (CE) method for the chiral discrimination of amlodipine (AML) enantiomers using cyclodextrine (CD) derivatives as chiral selectors. A large number of native and derivatized, neutral and ionized CD derivatives were screened to...