RNA-seq transcriptional profiling of Leishmania amazonensis reveals an arginase-dependent gene expression regulation.

• Main Authors: Juliana Ide Aoki (Author), Sandra Marcia Muxel (Author), Ricardo Andrade Zampieri (Author), Maria Fernanda Laranjeira-Silva (Author), Karl Erik Müller (Author), Audun Helge Nerland (Author), Lucile Maria Floeter-Winter (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmania is a protozoan parasite that alternates its life cycle between the sand-fly vector and the mammalian host. This alternation involves environmental changes and leads the parasite to dynamic modifications in morphology, metabolism, cellular signaling and regulation of gene expression to all...