The Discovery of Novel Agents against <i>Staphylococcus aureus</i> by Targeting Sortase A: A Combination of Virtual Screening and Experimental Validation

• Main Authors: Kang Liu (Author), Jiangbo Tong (Author), Xu Liu (Author), Dan Liang (Author), Fangzhe Ren (Author), Nan Jiang (Author), Zhenyu Hao (Author), Shixin Li (Author), Qiang Wang (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Staphylococcus aureus (S. aureus)</i>, commonly known as "superbugs", is a highly pathogenic bacterium that poses a serious threat to human health. There is an urgent need to replace traditional antibiotics with novel drugs to combat <i>S. aureus</i>. Sortase A (...