A tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma in vitro and in vivo

• Päätekijät: Shuai He (Tekijä), Bohong Cen (Tekijä), Lumin Liao (Tekijä), Zhen Wang (Tekijä), Yixin Qin (Tekijä), Zhuomin Wu (Tekijä), Wenjie Liao (Tekijä), Zhongyi Zhang (Tekijä), Aimin Ji (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The epidermal growth factor receptor (EGFR) is an important anti-tumor target. The development of novel molecular-targeted anti-tumor drugs that can target the interior of tumor cells and specifically silence EGFR expression is valuable and promising. In this work, a promising anti-tumor conjugate c...