A tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma in vitro and in vivo

• Main Authors: Shuai He (Author), Bohong Cen (Author), Lumin Liao (Author), Zhen Wang (Author), Yixin Qin (Author), Zhuomin Wu (Author), Wenjie Liao (Author), Zhongyi Zhang (Author), Aimin Ji (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The epidermal growth factor receptor (EGFR) is an important anti-tumor target. The development of novel molecular-targeted anti-tumor drugs that can target the interior of tumor cells and specifically silence EGFR expression is valuable and promising. In this work, a promising anti-tumor conjugate c...