Entamoeba lysyl-tRNA synthetase contains a cytokine-like domain with chemokine activity towards human endothelial cells.

• Main Authors: Manuel Castro de Moura (Author), Francesc Miro (Author), Jung Min Han (Author), Sunghoon Kim (Author), Antonio Celada (Author), Lluís Ribas de Pouplana (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immunological pressure encountered by protozoan parasites drives the selection of strategies to modulate or avoid the immune responses of their hosts. Here we show that the parasite Entamoeba histolytica has evolved a chemokine that mimics the sequence, structure, and function of the human cytokine...