Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors

Direct reprogramming of pancreatic nonendocrine cells into insulin-producing β-cells represents a promising approach for the treatment of insulin-dependent diabetes. However, its clinical application is limited by the potential for insertional mutagenesis associated with the viral vectors currently...

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Main Authors: Tomas Koblas (Author), Ivan Leontovyc (Author), Sarka Loukotova (Author), Lucie Kosinova (Author), Frantisek Saudek (Author)
Format: Book
Published: Elsevier, 2016-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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