Development of a Glycosaminoglycan Derived, Selectin Targeting Anti-Adhesive Coating to Treat Endothelial Cell Dysfunction

• मुख्य लेखकों: James R. Wodicka (लेखक), Andrea M. Chambers (लेखक), Gurneet S. Sangha (लेखक), Craig J. Goergen (लेखक), Alyssa Panitch (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2017-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Endothelial cell (EC) dysfunction is associated with many disease states including deep vein thrombosis (DVT), chronic kidney disease, sepsis and diabetes. Loss of the glycocalyx, a thin glycosaminoglycan (GAG)-rich layer on the EC surface, is a key feature of endothelial dysfunction and increases e...