Contribution of CFTR to Alveolar Fluid Clearance by Lipoxin A4 via PI3K/Akt Pathway in LPS-Induced Acute Lung Injury

• Main Authors: Yi Yang (Author), Yang Cheng (Author), Qing-Quan Lian (Author), Li Yang (Author), Wei Qi (Author), De-Rong Wu (Author), Xia Zheng (Author), Yong-Jian Liu (Author), Wen-Juan Li (Author), Sheng-Wei Jin (Author), Fang Gao Smith (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The lipoxins are the first proresolution mediators to be recognized and described as the endogenous "braking signals" for inflammation. We evaluated the anti-inflammatory and proresolution bioactions of lipoxin A4 in our lipopolysaccharide (LPS-)induced lung injury model. We demonstrated t...