Trichinella spiralis Paramyosin Binds Human Complement C1q and Inhibits Classical Complement Activation.

• Autori principali: Ran Sun (Autore), Xi Zhao (Autore), Zixia Wang (Autore), Jing Yang (Autore), Limei Zhao (Autore), Bin Zhan (Autore), Xinping Zhu (Autore)
• Natura: Libro
• Pubblicazione: Public Library of Science (PLoS), 2015-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

BACKGROUND:Trichinella spiralis expresses paramyosin (Ts-Pmy) as a defense mechanism. Ts-Pmy is a functional protein with binding activity to human complement C8 and C9 and thus plays a role in evading the attack of the host's immune system. In the present study, the binding activity of Ts-Pmy...