Trichinella spiralis Paramyosin Binds Human Complement C1q and Inhibits Classical Complement Activation.

• Hoofdauteurs: Ran Sun (Auteur), Xi Zhao (Auteur), Zixia Wang (Auteur), Jing Yang (Auteur), Limei Zhao (Auteur), Bin Zhan (Auteur), Xinping Zhu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2015-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

BACKGROUND:Trichinella spiralis expresses paramyosin (Ts-Pmy) as a defense mechanism. Ts-Pmy is a functional protein with binding activity to human complement C8 and C9 and thus plays a role in evading the attack of the host's immune system. In the present study, the binding activity of Ts-Pmy...