In Vivo siRNA Delivery Using JC Virus-like Particles Decreases the Expression of RANKL in Rats

• Main Authors: Daniel B Hoffmann (Author), Kai O Böker (Author), Stefan Schneider (Author), Ellen Eckermann-Felkl (Author), Angelina Schuder (Author), Marina Komrakova (Author), Stephan Sehmisch (Author), Jens Gruber (Author)
• Format: Book
• Published: Elsevier, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bone remodeling requires a precise balance between formation and resorption. This complex process involves numerous factors that orchestrate a multitude of biochemical events. Among these factors are hormones, growth factors, vitamins, cytokines, and, most notably, osteoprotegerin (OPG) and the rece...