Evaluation of the Effectiveness of Post-Stroke Metformin Treatment Using Permanent Middle Cerebral Artery Occlusion in Rats

• Main Authors: Gintare Zemgulyte (Author), Shigeru Tanaka (Author), Izumi Hide (Author), Norio Sakai (Author), Katryna Pampuscenko (Author), Vilmante Borutaite (Author), Daiva Rastenyte (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stroke is the second leading cause of death worldwide. Treatment options for ischemic stroke are limited, and the development of new therapeutic agents or combined therapies is imperative. Growing evidence suggests that metformin treatment, due to its anti-inflammatory action, exerts a neuroprotecti...