Decreased Regulatory T Cells in Vulnerable Atherosclerotic Lesions: Imbalance between Pro- and Anti-Inflammatory Cells in Atherosclerosis

• Main Authors: Ilonka Rohm (Author), Yevgeniya Atiskova (Author), Stefanie Drobnik (Author), Michael Fritzenwanger (Author), Daniel Kretzschmar (Author), Rudin Pistulli (Author), Jürgen Zanow (Author), Thomas Krönert (Author), Gita Mall (Author), Hans Reiner Figulla (Author), Atilla Yilmaz (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atherosclerosis is a chronic inflammatory disease of the arterial wall in which presentation of autoantigens by dendritic cells (DCs) leads to the activation of T cells. Anti-inflammatory cells like Tregs counterbalance inflammation in atherogenesis. In our study, human carotid plaque specimens were...