Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 Therapeutics

• Main Authors: Bérénice Charrez (Author), Verena Charwat (Author), Brian A. Siemons (Author), Ishan Goswami (Author), Courtney Sakolish (Author), Yu-Syuan Luo (Author), Henrik Finsberg (Author), Andrew G. Edwards (Author), Evan W. Miller (Author), Ivan Rusyn (Author), Kevin E. Healy (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite global efforts, it took 7 months between the proclamation of global SARS-CoV-2 pandemic and the first FDA-approved treatment for COVID-19. During this timeframe, clinicians focused their efforts on repurposing drugs, such as hydroxychloroquine (HCQ) or azithromycin (AZM) to treat hospitalize...