The Potential Protective Effect of Curcumin and α-Lipoic Acid on N-(4-Hydroxyphenyl) Acetamide-induced Hepatotoxicity Through Downregulation of α-SMA and Collagen III Expression

• Main Authors: Ahlam Alhusain (Author), Laila Fadda (Author), Wedad Sarawi (Author), Hatun Alomar (Author), Hanaa Ali (Author), Raeesa Mahamad (Author), Iman Hasan (Author), Amira Badr (Author)
• 格式: 图书
• 出版: SAGE Publishing, 2022-02-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Background and objectives N-(4-hydroxyphenyl) acetamide (NHPA) is the most commonly used analgesic and antipyretic agent worldwide; however, it remains the leading cause of drug-induced acute liver failure. This study explored the potential impact of curcumin (Curc) and/or α-lipoic acid (Lip acid) o...