Characterization of a single reporter-gene potency assay for T-cell-dependent bispecific molecules

• المؤلفون الرئيسيون: Ho Young Lee (مؤلف), Ames Register (مؤلف), Jeongsup Shim (مؤلف), Edward Contreras (مؤلف), Qiang Wu (مؤلف), Guoying Jiang (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2019-10-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

T-cell-dependent bispecific antibodies (TDBs) are promising cancer immunotherapies that recruit patients' T cells to kill cancer cells. There are many TDBs in clinical trials, demonstrating their widely recognized therapeutic potential. However, their complex, multi-step mechanism of action (Mo...