Oral lactate intensifies insulin toxicity during severe insulin-induced hypoglycemia in mice
ABSTRACT We investigated whether oral lactate could prevent seizures and deaths in mice with severe hypoglycemia induced by a high dose of insulin. For this purpose, mice were fasted for 15 h and then given an intraperitoneal injection of regular insulin (5.0 U/kg or 10.0 U/kg). Immediately after in...
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Main Authors: | Vanessa Rodrigues Vilela (Author), Marina Masetto Antunes (Author), Vilma Aparecida Ferreira Godoi (Author), Patricia Batista Travassos (Author), Helenir Medri de Souza (Author), Roberto Barbosa Bazotte (Author) |
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Format: | Book |
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Universidade de São Paulo,
2018-07-01T00:00:00Z.
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