CD14 Mediates Binding of High Doses of LPS but Is Dispensable for TNF-α Production
Activation of macrophages with lipopolysaccharide (LPS) involves a sequential engagement of serum LPS-binding protein (LBP), plasma membrane CD14, and TLR4/MD-2 signaling complex. We analyzed participation of CD14 in TNF-α production stimulated with 1-1000 ng/mL of smooth or rough LPS (sLPS or rLPS)...
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Format: | Book |
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Hindawi Limited,
2013-01-01T00:00:00Z.
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A1234.567 |
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