Safety, pharmacokinetics, and pharmacodynamics of ART‐648, a PDE4 inhibitor in healthy subjects: A randomized, placebo‐controlled phase I study
Abstract Phosphodiesterase 4 (PDE4) inhibitor is associated with a broad‐spectrum anti‐inflammatory mechanism. However, securing clinically efficacious doses with sufficient safety margins remains challenging due to class specific adverse events that are often unavoidable in the clinic. ART‐648 is a...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
Wiley,
2024-10-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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