Exploring the Thioredoxin System as a Therapeutic Target in Cancer: Mechanisms and Implications

• Main Authors: Rebecca Seitz (Author), Deniz Tümen (Author), Claudia Kunst (Author), Phillip Heumann (Author), Stephan Schmid (Author), Arne Kandulski (Author), Martina Müller (Author), Karsten Gülow (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cells constantly face the challenge of managing oxidants. In aerobic organisms, oxygen (O₂) is used for energy production, generating reactive oxygen species (ROS) as byproducts of enzymatic reactions. To protect against oxidative damage, cells possess an intricate system of r...