Biphasic effects of statins on neuron cell functions under oxygen-glucose deprivation and normal culturing conditions via different mechanisms

• Main Authors: Hui Wang (Author), Yun Chen (Author), Ping Li (Author), Yan Chen (Author), Danfang Yu (Author), Qian Tan (Author), Xiaoli Liu (Author), Zhenli Guo (Author)
• Format: Book
• Published: Wiley, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract While there is a growing interest in the use of statins, HMG‐CoA reductase inhibitors, to treat neurodegenerative diseases, statins are associated with conflicting effects within the central nervous system (CNS) without clear evidence of the underlying mechanisms. This study systematically...