Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Role of Rho-Kinase in the Development of Renal Injury

• Main Authors: Koichi Hayashi (Author), Shu Wakino (Author), Takeshi Kanda (Author), Koichiro Homma (Author), Naoki Sugano (Author), Takao Saruta (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Rho/Rho-kinase plays an important role not only in the vasoconstrictor mechanism but also in cellular morphology, motility, adhesion, and proliferation. This pathway also serves to modulate the structure and function of various kidney cells including tubular epithelial cells, mesangial ce...