Site-Directed Spin Labeling EPR Spectroscopy for Determination of Albumin Structural Damage and Hypoalbuminemia in Critical COVID-19

• Main Authors: Ekaterina Georgieva (Author), Yanka Karamalakova (Author), Georgi Arabadzhiev (Author), Vasil Atanasov (Author), Rositsa Kostandieva (Author), Mitko Mitev (Author), Vanya Tsoneva (Author), Yovcho Yovchev (Author), Galina Nikolova (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The main factors in the COVID-19 pathology, which can initiate extensive structural changes at the cellular and molecular levels, are the generation of free radicals in abnormal amounts, and oxidative stress. Under "oxidative shock" conditions, the proteins undergo various modifications th...