IL-33/ST2 correlates with severity of haemorrhagic fever with renal syndrome and regulates the inflammatory response in Hantaan virus-infected endothelial cells.

• Main Authors: Yusi Zhang (Author), Chunmei Zhang (Author), Ran Zhuang (Author), Ying Ma (Author), Yun Zhang (Author), Jing Yi (Author), Angang Yang (Author), Boquan Jin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hantaan virus (HTNV) causes a severe lethal haemorrhagic fever with renal syndrome (HFRS) in humans. Despite a limited understanding of the pathogenesis of HFRS, the importance of the abundant production of pro-inflammatory cytokines has been widely recognized. Interleukin 33 (IL-33) has been demons...