IL-33/ST2 correlates with severity of haemorrhagic fever with renal syndrome and regulates the inflammatory response in Hantaan virus-infected endothelial cells.

• Главные авторы: Yusi Zhang (Автор), Chunmei Zhang (Автор), Ran Zhuang (Автор), Ying Ma (Автор), Yun Zhang (Автор), Jing Yi (Автор), Angang Yang (Автор), Boquan Jin (Автор)
• Формат: ‌
• Опубликовано: Public Library of Science (PLoS), 2015-02-01T00:00:00Z.
• Предметы: article
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Hantaan virus (HTNV) causes a severe lethal haemorrhagic fever with renal syndrome (HFRS) in humans. Despite a limited understanding of the pathogenesis of HFRS, the importance of the abundant production of pro-inflammatory cytokines has been widely recognized. Interleukin 33 (IL-33) has been demons...