LNC473 Regulating APAF1 IRES-Dependent Translation via Competitive Sponging miR574 and miR15b: Implications in Colorectal Cancer

• Main Authors: Huizhe Wu (Author), Xiaoyun Hu (Author), Yalun Li (Author), Qiuchen Chen (Author), Tong Sun (Author), Yun Qiao (Author), Wenyan Qin (Author), Zhikun Wu (Author), Boshi Fu (Author), Haishan Zhao (Author), Rui Zhang (Author), Minjie Wei (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A growing number of studies have focused on the involvement of non-coding RNAs (ncRNAs) in the internal ribosome entry site (IRES)-mediated translation in tumorigenesis; however, the underlying mechanisms in colorectal cancer (CRC) remain elusive. In this study, we show that LINC00473 (LNC473) exert...