Feasibility of dendritic cell-based vaccine against glioblastoma by using cytoplasmic transduction peptide (CTP)-fused protein antigens combined with anti-PD1

• Main Authors: Young-Hee Kim (Author), Thi- (Author), Shin Jung (Author), In-Young Kim (Author), Kyung-Sub Moon (Author), Woo-Youl Jang (Author), Hyun-Ju Lee (Author), Je-Jung Lee (Author), Tae-Young Jung (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent clinical trials utilizing antigen-pulsed dendritic cells (DCs) have demonstrated increased survival of vaccinated cancer patients. Besides, the cytoplasmic transduction peptide (CTP) not only has an excellent transcellular efficiency but also shows a strong tendency to remain in the cytoplasm...