Models of enzyme inhibition and apparent dissociation constants from kinetic analysis to study the differential inhibition of aldose reductase

• Автори: Francesco Balestri (Автор), Mario Cappiello (Автор), Roberta Moschini (Автор), Umberto Mura (Автор), Antonella Del-Corso (Автор)
• Формат: Книга
• Опубліковано: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

In order to explain the negative slope of [Formula: see text] versus inhibitor concentration observed in the study of epigallocatechin gallate acting as an inhibitor of aldose reductase, a kinetic analysis was performed to rationalise the phenomenon. Classical and non-classical models of complete an...