Informing pregnancy dose via target‐mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody

Abstract RLYB212 is a human monoclonal anti‐human platelet antigen (HPA)‐1a immunoglobulin gamma 1 in clinical development as a subcutaneous injection for the prevention of maternal alloimmunization to fetal HPA‐1a leading to fetal and neonatal alloimmune thrombocytopenia (FNAIT). This analysis deve...

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Main Authors: Courtney Moc Willeford (Author), Krithika Shetty (Author), Douglas Sheridan (Author), Frank Engler (Author)
Format: Book
Published: Wiley, 2024-11-01T00:00:00Z.
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3rd Floor Main Library

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