The Annexin-A1 mimetic RTP-026 promotes acute cardioprotection through modulation of immune cell activation

• Hoofdauteurs: Jianmin Chen (Auteur), Silvia Oggero (Auteur), Chiara Cecconello (Auteur), Jesmond Dalli (Auteur), Hedayatullah Hayat (Auteur), Ahmad Hjiej Andaloussi (Auteur), Samra Sanni (Auteur), Thomas EN Jonassen (Auteur), Mauro Perretti (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2023-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Aims: The cardio-protective and immuno-regulatory properties of RTP-026, a synthetic peptide that spans the Annexin-A1 (AnxA1) N-terminal region, were tested in rat acute myocardial infarction. Methods and results: In vitro, selective activation of formyl-peptide receptor type 2 (FPR2) by RTP-026 oc...