Pomegranate peel extract protects against the development of diabetic cardiomyopathy in rats by inhibiting pyroptosis and downregulating LncRNA-MALAT1

• Main Authors: Mariam Ali Abo-Saif (Author), Amany E. Ragab (Author), Amera O. Ibrahim (Author), Othman F. Abdelzaher (Author), Ahmed B. M. Mehanyd (Author), Maha Saber-Ayad (Author), Ola A. El-Feky (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Pyroptosis is an inflammatory programmed cell death accompanied by activation of inflammasomes and maturation of pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18. Pyroptosis is closely linked to the development of diabetic cardiomyopathy (DC). Pomegranate peel extract (PPE) ex...