Anti-Inflammatory Effects of the Novel Barbiturate Derivative MHY2699 in an MPTP-Induced Mouse Model of Parkinson's Disease

• Main Authors: Seulah Lee (Author), Yeon Ji Suh (Author), Yujeong Lee (Author), Seonguk Yang (Author), Dong Geun Hong (Author), Dinakaran Thirumalai (Author), Seung-Cheol Chang (Author), Ki Wung Chung (Author), Young-Suk Jung (Author), Hyung Ryong Moon (Author), Hae Young Chung (Author), Jaewon Lee (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson's disease (PD) is one of the most common neurodegenerative disorders, and is caused by the death of dopamine neurons and neuroinflammation in the striatum and substantia nigra. Furthermore, the inflammatory response in PD is closely related to glial cell activation. This study examine...