Neuroprotective effect of acetoxypachydiol against oxidative stress through activation of the Keap1-Nrf2/HO-1 pathway

• Main Authors: Yu Qi (Author), Ge Liu (Author), Shengjie Jin (Author), Rong Jian (Author), Ziqiang Zou (Author), Chenjing Wang (Author), Yuanlong Zhang (Author), Min Zhao (Author), Haoru Zhu (Author), Pengcheng Yan (Author)
• Format: Book
• Published: BMC, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Excessive oxidative stress in the brain is an important pathological factor in neurological diseases. Acetoxypachydiol (APHD) is a lipophilic germacrane-type diterpene extracted as a major component from different species of brown algae within the genus Dictyota. There have been...