Aberrant Expression of ADARB1 Facilitates Temozolomide Chemoresistance and Immune Infiltration in Glioblastoma

• Main Authors: Can Lu (Author), Xi Chen (Author), Yuanliang Yan (Author), Xinxin Ren (Author), Xiang Wang (Author), Bi Peng (Author), Yuan Cai (Author), Qiuju Liang (Author), Zhijie Xu (Author), Jinwu Peng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemoresistance, especially temozolomide (TMZ) resistance, is a major clinical challenge in the treatment of glioblastoma (GBM). Exploring the mechanisms of TMZ resistance could help us identify effective therapies. Adenosine deaminases acting on RNA (ADARs) are very important in RNA modification th...