A Pegylated Liposomal Platform: Pharmacokinetics, Pharmacodynamics, and Toxicity in Mice Using Doxorubicin as a Model Drug

• Main Authors: Wan-Liang Lu (Author), Xian-Rong Qi (Author), Qiang Zhang (Author), Rong-Yu Li (Author), Gui-Lin Wang (Author), Rui-Juan Zhang (Author), Shu-Li Wei (Author)
• Format: Book
• Published: Elsevier, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims were to observe pharmacokinetics, pharmacodynamics, and toxicity for constructing a Sino-pegylated liposomal platform. Human hepatocarcinoma cells (Bel7402) and murine hepatocarcinoma cells (H22) were used for the cytotoxicity assay and the in vivo solid xenograft tumor model in mice, respectiv...