Ivermectin treatment of Loa loa hyper-microfilaraemic baboons (Papio anubis): Assessment of microfilarial load reduction, haematological and biochemical parameters and histopathological changes following treatment.

• Hauptverfasser: Samuel Wanji (Verfasst von), Ebanga-Echi J Eyong (Verfasst von), Nicholas Tendongfor (Verfasst von), Che J Ngwa (Verfasst von), Elive N Esuka (Verfasst von), Arnaud J Kengne-Ouafo (Verfasst von), Fabrice R Datchoua-Poutcheu (Verfasst von), Peter Enyong (Verfasst von), Dalen Agnew (Verfasst von), Rob R Eversole (Verfasst von), Adrian Hopkins (Verfasst von), Charles D Mackenzie (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2017-07-01T00:00:00Z.
• Schlagworte: article
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Individuals with high intensity of Loa loa are at risk of developing serious adverse events (SAEs) post treatment with ivermectin. These SAEs have remained unclear and a programmatic impediment to the advancement of community directed treatment with ivermectin. The pathogenesis of these SAEs followi...