Biodistribution of a Radiolabeled Antibody in Mice as an Approach to Evaluating Antibody Pharmacokinetics

• 主要な著者: Kevin J. H. Allen (著者), Rubin Jiao (著者), Mackenzie E. Malo (著者), Connor Frank (著者), Ekaterina Dadachova (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2018-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

(1) Background: Monoclonal antibodies are used in the treatment of multiple conditions including cancer, autoimmune disorders, and infectious diseases. One of the initial steps in the selection of an antibody candidate for further pre-clinical development is determining its pharmacokinetics in small...