Genetic modifiers of Hb E/β⁰thalassemia identified by a two-stage genome-wide association study

• Main Authors: Winichagoon Pranee (Author), Makarasara Wattanan (Author), Angkachatchai Vach (Author), Whitacre Johanna (Author), Ma Qianli (Author), Abel Kenneth (Author), Sripichai Orapan (Author), Sherva Richard (Author), Svasti Saovaros (Author), Fucharoen Suthat (Author), Braun Andreas (Author), Farrer Lindsay A (Author)
• Format: Book
• Published: BMC, 2010-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Patients with Hb E/β⁰thalassemia display remarkable variability in disease severity. To identify genetic modifiers influencing disease severity, we conducted a two-stage genome scan in groups of 207 mild and 3...