Superoxide induces Neutrophil Extracellular Trap Formation in a TLR-4 and NOX-Dependent Mechanism

• Główni autorzy: Ahmed B Al-Khafaji (Autor), Samer Tohme (Autor), Hamza Obaid Yazdani (Autor), David Miller (Autor), Hai Huang (Autor), Allan Tsung (Autor)
• Format: Książka
• Wydane: BMC, 2016-07-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Neutrophils constitute the early innate immune response to perceived infectious and sterile threats. Neutrophil extracellular traps (NETs) are a novel mechanism to counter pathogenic invasion and sequelae of ischemia, including cell death and oxidative stress. Superoxide is a radical interm...