Protective Effect of Gabapentin on N-methyl-D-aspartate-Induced Excitotoxicity in Rat Hippocampal CA1 Neurons

• Main Authors: Young-Sick Kim (Author), Hyun-Kyung Chang (Author), Jin-Woo Lee (Author), Yun-Hee Sung (Author), Sung-Eun Kim (Author), Mal-Soon Shin (Author), Jae-Woo Yi (Author), Je-Hoon Park (Author), Hong Kim (Author), Chang-Ju Kim (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gabapentin was developed as an anticonvulsant, but has also been used to alleviate hyperalgesia in neuropathic pain. In this study, the protective effect of gabapentin against N-methyl-D-aspartate (NMDA)-induced excitotoxicity in rat hippocampal CA1 neurons was investigated. Pre-treatment with gabap...