Carbonic anhydrase inhibition with a series of novel benzenesulfonamide-triazole conjugates

• Egile Nagusiak: Marwa G. El-Gazzar (Egilea), Nessma H. Nafie (Egilea), Alessio Nocentini (Egilea), Mostafa M. Ghorab (Egilea), Helmi I. Heiba (Egilea), Claudiu T. Supuran (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

We report the synthesis and characterisation of a novel series of triazole benzenesulfonamide derivatives, which incorporate the general pharmacophore associated with carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. The synthesised compounds were tested in vitro against four human carbonic anhydrase...