Adeno-Associated Viral Vector-Mediated mTOR Inhibition by Short Hairpin RNA Suppresses Laser-Induced Choroidal Neovascularization

• Main Authors: Tae Kwann Park (Author), Si Hyung Lee (Author), Jun Sub Choi (Author), Seung Kwan Nah (Author), Hee Jong Kim (Author), Ha Yan Park (Author), Heuiran Lee (Author), Steven Hyun Seung Lee (Author), Keerang Park (Author)
• Format: Book
• Published: Elsevier, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Choroidal neovascularization (CNV) is the defining characteristic feature of the wet subtype of age-related macular degeneration (AMD) and may result in irreversible blindness. Based on anti-vascular endothelial growth factor (anti-VEGF), the current therapeutic approaches to CNV are fraught with di...