Exosomes derived from pulmonary metastatic sites enhance osteosarcoma lung metastasis by transferring the miR-194/215 cluster targeting MARCKS

• Main Authors: Pei Yu (Author), Yubao Han (Author), Lulu Meng (Author), Yanyuan Tian (Author), Zhiwei Jin (Author), Jun Luo (Author), Chao Han (Author), Wenjun Xu (Author), Lingyi Kong (Author), Chao Zhang (Author)
• Format: Book
• Published: Elsevier, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteosarcoma, a prevalent primary malignant bone tumor, often presents with lung metastases, severely impacting patient survival rates. Extracellular vesicles, particularly exosomes, play a pivotal role in the formation and progression of osteosarcoma-related pulmonary lesions. However, the communic...