The cell-permeant antioxidant D-thiol ester D-cysteine ethyl ester overcomes physical dependence to morphine in male Sprague Dawley rats

The cell-permeant antioxidant D-thiol ester D-cysteine ethyl ester overcomes physical dependence to morphine in male Sprague Dawley rats

The ability of morphine to decrease cysteine transport into neurons by inhibition of excitatory amino acid transporter 3 (EAA3) may be a key molecular mechanism underlying the acquisition of physical and psychological dependence to morphine. This study examined whether co-administration of the cell-...

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Main Authors: Paulina M. Getsy (Author), Gregory A. Coffee (Author), James N. Bates (Author), Theodore Parran (Author), Lee Hoffer (Author), Santhosh M. Baby (Author), Peter M. MacFarlane (Author), Zackery T. Knauss (Author), Derek S. Damron (Author), Yee-Hsee Hsieh (Author), Jason A. Bubier (Author), Devin Mueller (Author), Stephen J. Lewis (Author)
Format: Book
Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
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3rd Floor Main Library

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