Combined in vitro IL-12 and IL-15 stimulation promotes cellular immune response in dogs with visceral leishmaniasis.

• Main Authors: Sidnei Ferro Costa (Author), Vinícius Oliveira Gomes (Author), Marilene Oliveira Dos Santos Maciel (Author), Larissa Martins Melo (Author), Gabriela Lovizutto Venturin (Author), Jaqueline Poleto Bragato (Author), Gabriela Torres Rebech (Author), Catiule de Oliveira Santos (Author), Bárbara Maria Nascimento de Oliveira (Author), Geraldo Gileno de Sá Oliveira (Author), Valéria Marçal Felix de Lima (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Domestic dogs are the main reservoir of Leishmania infantum, a causative agent of visceral leishmaniasis (VL). The number of human disease cases is associated with the rate of canine infection. Currently available drugs are not efficient at treating canine leishmaniasis (CanL) and months after the t...