Dual Regulation of Voltage-Sensitive Ion Channels by PIP2

• Main Authors: Aldo A Rodríguez Menchaca (Author), Scott K Adney (Author), Lei eZhou (Author), Diomedes E Logothetis (Author)
• Format: Book
• Published: Frontiers Media S.A., 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Over the past 16 years, there has been an impressive number of ion channels shown to be sensitive to the major phosphoinositide in the plasma membrane, phosphatidilinositol 4,5-bisphosphate (PIP2). Among them are voltage-gated channels, which are crucial for both neuronal and cardiac excitability. V...