Characterization of Plasma Protein Alterations in Pregnant and Postpartum Individuals Living With HIV to Support Physiologically-Based Pharmacokinetic Model Development

Background: Alterations in plasma protein concentrations in pregnant and postpartum individuals can influence antiretroviral (ARV) pharmacokinetics. Physiologically-based pharmacokinetic (PBPK) models can serve to inform drug dosing decisions in understudied populations. However, development of such...

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Main Authors: Sherry Zhao (Author), Mary Gockenbach (Author), Manuela Grimstein (Author), Hari Cheryl Sachs (Author), Mark Mirochnick (Author), Kimberly Struble (Author), Yodit Belew (Author), Jian Wang (Author), Edmund V. Capparelli (Author), Brookie M. Best (Author), Tamara Johnson (Author), Jeremiah D. Momper (Author), Anil R. Maharaj (Author)
Formato: Livro
Publicado em: Frontiers Media S.A., 2021-10-01T00:00:00Z.
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