Recombinant paracoccin reproduces the biological properties of the native protein and induces protective Th1 immunity against Paracoccidioides brasiliensis infection.

BACKGROUND: Paracoccin is a dual-function protein of the yeast Paracoccidioides brasiliensis that has lectin properties and N-acetylglucosaminidase activities. Proteomic analysis of a paracoccin preparation from P. brasiliensis revealed that the sequence matched that of the hypothetical protein enco...

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Hoofdauteurs: Ana Claudia Paiva Alegre (Auteur), Aline Ferreira Oliveira (Auteur), Fausto Bruno Dos Reis Almeida (Auteur), Maria Cristina Roque-Barreira (Auteur), Ebert Seixas Hanna (Auteur)
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Gepubliceerd in: Public Library of Science (PLoS), 2014-04-01T00:00:00Z.
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