Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

• Main Authors: Gallagher Michael F (Author), Heffron Cynthia CBB (Author), Laios Alexandros (Author), O'Toole Sharon A (Author), Ffrench Brendan (Author), Smyth Paul C (Author), Flavin Richard J (Author), Elbaruni Salah A (Author), Spillane Cathy D (Author), Martin Cara M (Author), Sheils Orla M (Author), O'Leary John J (Author)
• Format: Book
• Published: BMC, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Malignant ovarian disease is characterised by high rates of mortality due to high rates of recurrent chemoresistant disease. Anecdotal evidence indicates this may be due to chemoresistant properties of cancer stem cells (CSCs). Howev...